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Browse somatic cancers
by tissues or terms ...
NCI-60 cancer cell lines
Browse cancer-related
KEGG pathways ...
....
Find target by gene identifier
Find targets by list of
gene identifiers
Browse cancer-related
KEGG pathways
Find targets by NCI-60
gene expression ...
... using a gene identifier
... using a KEGG pathway
... using significant
gene expression in 1 to 7
single NCI-60 cell lines
Find targets by
differential gene expression ...
... within 2 NCI-60 cell lines
... from one own/external expression data set against one NCI-60 cell line
... from one own/external expression data set to
determine the the closest NCI-60 cancer cell line
... from two own/external expression data sets
(e.g., cancer/normal)
... from own/external expression data
using pre-calculated ratios
Connectivity Map ...
... explore drug influence on
differential gene expression
Find drugs ...
... by identifier
... by chemical property
... by structure
Find drugs by similarity
in growth activity of NCI-60 cancer cell lines (cellular fingerprints) ...
... using a compound identifier
... of a compound group
... manually defining a
cellular fingerprint
... defining and searching by a compound structure
Find drugs most
biologically active against
a NCI-60 cancer cell line
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doi: 10.1093/nar/gkq910
Target search: 1 gene found
Erythropoietin receptor
(ENSG00000187266 - EPOR - P19235 A9QVL7)
Cancer relevance of EPOR (ENSG00000187266)
Cancer-related Pathways for KEGG gene
2057
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
Cancer-related Literature
133100
(phenotype)
133171
(gene)
Cancer Types
from drug target interaction databases
prostate
Connectivity Map
Drug Treatment - Expression Data
ENSG00000187266
NCI-60
expression for ENSG00000187266
cancer cell lines
37986_at
396_f_at
209962_at
209963_s_at
mean
NCI-60
expression of PPI partners of ...
ENSG00000187266
Drugs interacting with EPOR (ENSG00000187266)
Epoetin Alfa
DrugBank
PMID
(22 citations)
Erythropoietin
DrugBank
PMID
(22 citations)
gefitinib
CTD
PMID
16685379
Drug interactions of PPI partners of ...
P19235
← explore drug target interactions of protein-protein-interaction partners
Protein information from multiple resources on EPOR (ENSG00000187266)
Target protein
P19235 - EPOR_HUMAN
Description
Erythropoietin receptor
Synonyms
EPO-R
virtual access to literature search results
P19235
Protein complex association
EPOR receptor complex
EPO-EPOR complex
Protein Identifier
EPOR_HUMAN
Protein Accession Number
P19235
Gene Symbol
EPOR
Gene ID
ENSG00000187266
Protein ID
ENSP00000222139
Variations (Gene as map --- transcript as list)
ENSG00000187266
---
ENST00000222139
Structure Information
2JIX
-
1EBP
-
1EBA
-
1CN4
-
1ERN
-
1EER
Domain family
fn3
Gene ID
2057
virtual access to biological pathways
P19235
Protein-protein interaction (PPI) partners of ...
P19235
← O14508 P21583 P32927 O14543 P19235
Target protein
A9QVL7 - A9QVL7_HUMAN
virtual access to literature search results
A9QVL7
Protein Identifier
A9QVL7_HUMAN
Protein Accession Number
A9QVL7
Gene Symbol
EPOR
Gene ID
ENSG00000187266
Protein ID
ENSP00000222139
Variations (Gene as map --- transcript as list)
ENSG00000187266
---
ENST00000222139
virtual access to biological pathways
A9QVL7