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Browse somatic cancers
by tissues or terms ...
NCI-60 cancer cell lines
Browse cancer-related
KEGG pathways ...
....
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gene identifiers
Browse cancer-related
KEGG pathways
Find targets by NCI-60
gene expression ...
... using a gene identifier
... using a KEGG pathway
... using significant
gene expression in 1 to 7
single NCI-60 cell lines
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differential gene expression ...
... within 2 NCI-60 cell lines
... from one own/external expression data set against one NCI-60 cell line
... from one own/external expression data set to
determine the the closest NCI-60 cancer cell line
... from two own/external expression data sets
(e.g., cancer/normal)
... from own/external expression data
using pre-calculated ratios
Connectivity Map ...
... explore drug influence on
differential gene expression
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... by identifier
... by chemical property
... by structure
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in growth activity of NCI-60 cancer cell lines (cellular fingerprints) ...
... using a compound identifier
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doi: 10.1093/nar/gkq910
Target search: 1 gene found
Fibrinogen alpha chain
(ENSG00000171560 - FGA - P02671 A8K3E4 Q6NSD8 Q86Z09 Q8WW76)
Cancer relevance of FGA (ENSG00000171560)
Cancer-related Pathways for KEGG gene
2243
Complement and coagulation cascades
Cancer-related Literature
105200
(phenotype)
134820
(gene+phenotype)
202400
(phenotype)
Connectivity Map
Drug Treatment - Expression Data
ENSG00000171560
NCI-60
expression for ENSG00000171560
cancer cell lines
205649_s_at
205650_s_at
mean
NCI-60
expression of PPI partners of ...
ENSG00000171560
Drugs interacting with FGA (ENSG00000171560)
benzamidine
DrugBank
PMID
(26 citations)
carebastine
DrugBank
PMID
(26 citations)
Mannose
DrugBank
PMID
(26 citations)
Sucralfate
DrugBank
PMID
(26 citations)
Tenecteplase
DrugBank
PMID
(26 citations)
Anistreplase
DrugBank
PMID
(26 citations)
Drug interactions of PPI partners of ...
P02671
← explore drug target interactions of protein-protein-interaction partners
Protein information from multiple resources on FGA (ENSG00000171560)
Target protein
P02671 - FIBA_HUMAN
Description
Fibrinogen alpha chain
Synonyms
Fibrinopeptide A
virtual access to literature search results
P02671
Protein Identifier
FIBA_HUMAN
Protein Accession Number
P02671
Gene Symbol
FGA
Gene ID
ENSG00000171560
Protein ID
ENSP00000306361
Variations (Gene as map --- transcript as list)
ENSG00000171560
---
ENST00000302053
Structure Information
1RF1
-
1FZB
-
1LT9
-
1FZC
-
2Q9I
-
1N8E
-
3GHG
-
2HPC
-
2HLO
-
1RE4
-
1N86
-
1RE3
-
1FZA
-
2A45
-
1LTJ
-
1FZD
-
1FZG
-
2FFD
-
1FZF
-
2OYH
-
1FZE
-
1RF0
-
3E1I
-
3BVH
-
2OYI
-
2H43
-
2Z4E
-
3HUS
-
3H32
-
2HOD
-
1YCP
-
1BBR
Domain families
Fibrinogen_C
-
Fibrinogen_aC
-
Fib_alpha
Gene ID
2243
virtual access to biological pathways
P02671
Protein-protein interaction (PPI) partners of ...
P02671
← P02675 P02679 Q92876 P05154 P02671 P07996 P00488 P14543 P00750
Target protein
A8K3E4 - A8K3E4_HUMAN
virtual access to literature search results
A8K3E4
Protein Identifier
A8K3E4_HUMAN
Protein Accession Number
A8K3E4
Gene Symbol
FGA
Gene ID
ENSG00000171560
Protein ID
ENSP00000385981
Variations (Gene as map --- transcript as list)
ENSG00000171560
---
ENST00000403106
Domain families
Fibrinogen_aC
-
Fib_alpha
virtual access to biological pathways
A8K3E4
Target protein
Q6NSD8 - Q6NSD8_HUMAN
virtual access to literature search results
Q6NSD8
Protein Identifier
Q6NSD8_HUMAN
Protein Accession Number
Q6NSD8
Gene Symbol
FGA
Gene ID
ENSG00000171560
Protein ID
ENSP00000407891
Variations (Gene as map --- transcript as list)
ENSG00000171560
---
ENST00000457487
Domain family
Fib_alpha
virtual access to biological pathways
Q6NSD8
Target protein
Q86Z09 - Q86Z09_HUMAN
virtual access to literature search results
Q86Z09
Protein Identifier
Q86Z09_HUMAN
Protein Accession Number
Q86Z09
Gene Symbol
FGA
Gene ID
ENSG00000171560
Protein IDs
ENSP00000384151
,
ENSP00000407891
,
ENSP00000415653
,
ENSP00000306361
,
ENSP00000385981
Variations (Gene as map --- transcript as list)
ENSG00000171560
---
ENST00000457487
,
ENST00000457487
,
ENST00000414783
,
ENST00000302053
,
ENST00000403106
Domain family
Fib_alpha
virtual access to biological pathways
Q86Z09
Target protein
Q8WW76 - Q8WW76_HUMAN
virtual access to literature search results
Q8WW76
Protein Identifier
Q8WW76_HUMAN
Protein Accession Number
Q8WW76
Gene Symbol
FGA
Gene ID
ENSG00000171560
Protein ID
ENSP00000415653
Variations (Gene as map --- transcript as list)
ENSG00000171560
---
ENST00000414783
Domain family
Fib_alpha
virtual access to biological pathways
Q8WW76