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Browse somatic cancers
by tissues or terms ...
NCI-60 cancer cell lines
Browse cancer-related
KEGG pathways ...
....
Find target by gene identifier
Find targets by list of
gene identifiers
Browse cancer-related
KEGG pathways
Find targets by NCI-60
gene expression ...
... using a gene identifier
... using a KEGG pathway
... using significant
gene expression in 1 to 7
single NCI-60 cell lines
Find targets by
differential gene expression ...
... within 2 NCI-60 cell lines
... from one own/external expression data set against one NCI-60 cell line
... from one own/external expression data set to
determine the the closest NCI-60 cancer cell line
... from two own/external expression data sets
(e.g., cancer/normal)
... from own/external expression data
using pre-calculated ratios
Connectivity Map ...
... explore drug influence on
differential gene expression
Find drugs ...
... by identifier
... by chemical property
... by structure
Find drugs by similarity
in growth activity of NCI-60 cancer cell lines (cellular fingerprints) ...
... using a compound identifier
... of a compound group
... manually defining a
cellular fingerprint
... defining and searching by a compound structure
Find drugs most
biologically active against
a NCI-60 cancer cell line
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doi: 10.1093/nar/gkq910
Target search: 1 gene found
Interleukin-13
(ENSG00000169194 - IL13 - P35225 Q4VB50 Q4VB51 Q4VB53)
Cancer relevance of IL13 (ENSG00000169194)
Cancer-related Pathways for KEGG gene
3596
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
Cancer-related Literature
607154
(phenotype)
147683
(gene)
Cancer Types
from drug target interaction databases
skin
Connectivity Map
Drug Treatment - Expression Data
ENSG00000169194
NCI-60
expression for ENSG00000169194
No query result. No gene or expression corresponding to input found in database ...
NCI-60
expression of PPI partners of ...
ENSG00000169194
Drugs interacting with IL13 (ENSG00000169194)
interferon alfacon-1
PharmGKB
PMID
17602083
Drug interactions of PPI partners of ...
P35225
← explore drug target interactions of protein-protein-interaction partners
Protein information from multiple resources on IL13 (ENSG00000169194)
Target protein
P35225 - IL13_HUMAN
Description
Interleukin-13
Synonyms
IL-13
virtual access to literature search results
P35225
Protein Identifier
IL13_HUMAN
Protein Accession Number
P35225
Gene Symbol
IL13
Gene ID
ENSG00000169194
Protein ID
ENSP00000304915
Variations (Gene as map --- transcript as list)
ENSG00000169194
---
ENST00000304506
Structure Information
1IK0
-
3ITR
-
3ITS
-
3G6D
-
3BPO
-
1J9U
-
1IJZ
-
1GA3
Domain family
IL13
Gene ID
3596
virtual access to biological pathways
P35225
Protein-protein interaction (PPI) partners of ...
P35225
← P24394
Target protein
Q4VB50 - Q4VB50_HUMAN
virtual access to literature search results
Q4VB50
Protein Identifier
Q4VB50_HUMAN
Protein Accession Number
Q4VB50
Gene Symbol
IL13
Gene ID
ENSG00000169194
Protein ID
ENSP00000304915
Variations (Gene as map --- transcript as list)
ENSG00000169194
---
ENST00000304506
Domain family
IL13
virtual access to biological pathways
Q4VB50
Target protein
Q4VB51 - Q4VB51_HUMAN
virtual access to literature search results
Q4VB51
Protein Identifier
Q4VB51_HUMAN
Protein Accession Number
Q4VB51
Gene Symbol
IL13
Gene ID
ENSG00000169194
Protein ID
ENSP00000304915
Variations (Gene as map --- transcript as list)
ENSG00000169194
---
ENST00000304506
virtual access to biological pathways
Q4VB51
Target protein
Q4VB53 - Q4VB53_HUMAN
virtual access to literature search results
Q4VB53
Protein Identifier
Q4VB53_HUMAN
Protein Accession Number
Q4VB53
Gene Symbol
IL13
Gene ID
ENSG00000169194
Protein ID
ENSP00000304915
Variations (Gene as map --- transcript as list)
ENSG00000169194
---
ENST00000304506
virtual access to biological pathways
Q4VB53