Target search: 1 gene found

Sphingomyelin phosphodiesterase (ENSG00000166311 - SMPD1 - P17405 A8K8M3 Q59EN6 Q8IUN0)
Cancer relevance of SMPD1 (ENSG00000166311)
OMIM ® - Online Mendelian Inheritance in Man Cancer-related Literature 257200  (phenotype)
607608  (gene)
607616  (phenotype)
Cancer Types from drug target interaction databases various
Connectivity Map  info  Drug Treatment - Expression Data ENSG00000166311   info
NCI-60 expression for ENSG00000166311  info
 cancer cell lines                                                                                                                         
209420_s_at                                                                                                                        
216230_x_at                                                                                                                        
mean                                                                                                                        
Drugs interacting with SMPD1 (ENSG00000166311)
Desipramine DrugBank PMID    (19 citations)
Doxorubicin PharmGKB PMID    10463940
Protein information from multiple resources on SMPD1 (ENSG00000166311)
Target protein P17405 - ASM_HUMAN
Description Sphingomyelin phosphodiesterase
Synonyms aSMase - Acid sphingomyelinase
iHOP - Information Hyperlinked over Proteins virtual access to literature search results P17405
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier ASM_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number P17405
HUGO Gene Nomenclature Committee Gene Symbol SMPD1
Ensembl: gene information Gene ID ENSG00000166311
Ensembl: protein information Protein ID ENSP00000340409
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000166311 --- ENST00000342245
Pfam database - a large collection of protein families Domain family Metallophos
KEGG: Kyoto Encyclopedia of Genes and Genomes Gene ID 6609
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways P17405
SYSTERS release 4 - large-scale protein clustering based on sequence similarity for the entire organism space Protein Sequence Family 147132 (for P17405)

Target protein A8K8M3 - A8K8M3_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results A8K8M3
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier A8K8M3_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number A8K8M3
HUGO Gene Nomenclature Committee Gene Symbol SMPD1
Ensembl: gene information Gene ID ENSG00000166311
Ensembl: protein information Protein ID ENSP00000340409
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000166311 --- ENST00000342245
Pfam database - a large collection of protein families Domain family Metallophos
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways A8K8M3

Target protein Q59EN6 - Q59EN6_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results Q59EN6
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier Q59EN6_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number Q59EN6
HUGO Gene Nomenclature Committee Gene Symbol SMPD1
Ensembl: gene information Gene ID ENSG00000166311
Ensembl: protein information Protein ID ENSP00000340409
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000166311 --- ENST00000342245
Pfam database - a large collection of protein families Domain family Metallophos
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways Q59EN6

Target protein Q8IUN0 - Q8IUN0_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results Q8IUN0
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier Q8IUN0_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number Q8IUN0
HUGO Gene Nomenclature Committee Gene Symbol SMPD1
Ensembl: gene information Gene ID ENSG00000166311
Ensembl: protein information Protein IDs ENSP00000299397, ENSP00000349203, ENSP00000340409
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000166311 --- ENST00000299397, ENST00000299397, ENST00000342245
Pfam database - a large collection of protein families Domain family Metallophos
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways Q8IUN0
SYSTERS release 4 - large-scale protein clustering based on sequence similarity for the entire organism space Protein Sequence Family 147132 (for Q8IUN0)