Target search: 1 gene found

Tyrosine-protein kinase receptor Mast/stem cell growth factor receptor (ENSG00000157404 - KIT - Q6IQ28 P10721 B5A956 B6DXN3 B6E0M6 Q14708 Q14709 Q8TCG9)
Cancer relevance of KIT (ENSG00000157404)
KEGG: Kyoto Encyclopedia of Genes and GenomesCancer-related Pathways for KEGG gene 3815 Acute myeloid leukemia
Cytokine-cytokine receptor interaction
OMIM ® - Online Mendelian Inheritance in Man Cancer-related Literature 172800  (phenotype)
273300  (phenotype)
606764  (phenotype)
164920  (gene)
Cancer Types from drug target interaction databases brain, breast, leukemia, lung, pancreatic, skin, stomach, various
Connectivity Map  info  Drug Treatment - Expression Data ENSG00000157404   info
NCI-60 expression for ENSG00000157404  info
 cancer cell lines                                                                                                                         
205051_s_at                                                                                                                        
ConsensusPathDB - information on physical molecular interactions, biochemical pathways, and gene regulatory networks NCI-60 expression of PPI partners of ... ENSG00000157404
Drugs interacting with KIT (ENSG00000157404)
dasatinib DrugBank PMID    (12 citations)
Cisplatin PharmGKB PMID    18379348
gefitinib PharmGKB PMID    18379348
imatinib PharmGKB PMID    (4 citations)
TTD drug ID    DAP000179
DrugBank PMID    (12 citations)
Sunitinib PharmGKB PMID    (3 citations)
TTD drug ID    (2 citations)
DrugBank PMID    (12 citations)
Sorafenib DrugBank PMID    (12 citations)
Motesanib TTD drug ID    DCL000578
Phosphotyrosine DrugBank PMID    (12 citations)
ADP DrugBank PMID    (12 citations)
Adaphostin PDB structure    (3 ligand interactions)
ConsensusPathDB - information on physical molecular interactions, biochemical pathways, and gene regulatory networks Drug interactions of PPI partners of ... P10721 ← explore drug target interactions of protein-protein-interaction partners
Protein information from multiple resources on KIT (ENSG00000157404)
Target protein Q6IQ28 - Q6IQ28_HUMAN
Description Tyrosine-protein kinase receptor
iHOP - Information Hyperlinked over Proteins virtual access to literature search results Q6IQ28
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier Q6IQ28_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number Q6IQ28
HUGO Gene Nomenclature Committee Gene Symbol KIT
Ensembl: gene information Gene ID ENSG00000157404
Ensembl: protein information Protein ID ENSP00000288135
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000157404 --- ENST00000288135
Pfam database - a large collection of protein families Domain families ig -  Pkinase_Tyr
KEGG: Kyoto Encyclopedia of Genes and Genomes Gene ID 3815
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways Q6IQ28
Target protein P10721 - KIT_HUMAN
Description Mast/stem cell growth factor receptor
Synonyms SCFR - Proto-oncogene c-Kit - Tyrosine-protein kinase Kit
iHOP - Information Hyperlinked over Proteins virtual access to literature search results P10721
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier KIT_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number P10721
HUGO Gene Nomenclature Committee Gene Symbol KIT
Ensembl: gene information Gene ID ENSG00000157404
Ensembl: protein information Protein ID ENSP00000288135
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000157404 --- ENST00000288135
PDB - A Resource for Studying Biological Macromolecules Structure Information 3G0E - 1R01 - 1QZK - 1T45 - 2E9W - 2EC8 - 2VIF - 1PKG - 1QZJ - 1T46 - 3G0F
Pfam database - a large collection of protein families Domain families ig -  Pkinase_Tyr
KEGG: Kyoto Encyclopedia of Genes and Genomes Gene ID 3815
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways P10721
ConsensusPathDB - information on physical molecular interactions, biochemical pathways, and gene regulatory networks Protein-protein interaction (PPI) partners of ... P10721 ← P21583 Q06187 P32927 O14544 O15524 P19235 P10721 P15509
Target protein B5A956 - B5A956_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results B5A956
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier B5A956_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number B5A956
HUGO Gene Nomenclature Committee Gene Symbol KIT
Ensembl: gene information Gene ID ENSG00000157404
Ensembl: protein information Protein IDs ENSP00000390987, ENSP00000288135
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000157404 --- ENST00000412167, ENST00000288135
Pfam database - a large collection of protein families Domain family ig
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways B5A956
Target protein B6DXN3 - B6DXN3_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results B6DXN3
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier B6DXN3_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number B6DXN3
HUGO Gene Nomenclature Committee Gene Symbol KIT
Ensembl: gene information Gene ID ENSG00000157404
Ensembl: protein information Protein IDs ENSP00000390987, ENSP00000288135
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000157404 --- ENST00000412167, ENST00000288135
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways B6DXN3
Target protein B6E0M6 - B6E0M6_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results B6E0M6
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier B6E0M6_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number B6E0M6
HUGO Gene Nomenclature Committee Gene Symbol KIT
Ensembl: gene information Gene ID ENSG00000157404
Ensembl: protein information Protein IDs ENSP00000390987, ENSP00000288135
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000157404 --- ENST00000412167, ENST00000288135
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways B6E0M6
Target protein Q14708 - Q14708_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results Q14708
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier Q14708_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number Q14708
HUGO Gene Nomenclature Committee Gene Symbol KIT
Ensembl: gene information Gene ID ENSG00000157404
Ensembl: protein information Protein ID ENSP00000288135
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000157404 --- ENST00000288135
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways Q14708
Target protein Q14709 - Q14709_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results Q14709
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier Q14709_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number Q14709
HUGO Gene Nomenclature Committee Gene Symbol KIT
Ensembl: gene information Gene ID ENSG00000157404
Ensembl: protein information Protein ID ENSP00000390987
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000157404 --- ENST00000412167
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways Q14709
Target protein Q8TCG9 - Q8TCG9_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results Q8TCG9
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier Q8TCG9_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number Q8TCG9
HUGO Gene Nomenclature Committee Gene Symbol KIT
Ensembl: gene information Gene ID ENSG00000157404
Ensembl: protein information Protein IDs ENSP00000390987, ENSP00000288135
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000157404 --- ENST00000412167, ENST00000288135
Pfam database - a large collection of protein families Domain family Pkinase_Tyr
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways Q8TCG9