Target search: 1 gene found

Pyruvate kinase isozymes R/L Pyruvate kinase (ENSG00000143627 - PKLR - P30613 B1AVT1 B1AVT2 B4DPM0 O75758 Q16715 Q16716)
Cancer relevance of PKLR (ENSG00000143627)
OMIM ® - Online Mendelian Inheritance in Man Cancer-related Literature 266200  (phenotype)
609712  (gene)
102900  (phenotype)
Connectivity Map  info  Drug Treatment - Expression Data ENSG00000143627   info
NCI-60 expression for ENSG00000143627  info
 cancer cell lines                                                                                                                         
207858_s_at                                                                                                                        
210451_at                                                                                                                        
222078_at                                                                                                                        
mean                                                                                                                        
ConsensusPathDB - information on physical molecular interactions, biochemical pathways, and gene regulatory networks NCI-60 expression of PPI partners of ... ENSG00000143627
Drugs interacting with PKLR (ENSG00000143627)
phosphoglycolate DrugBank PMID    (21 citations)
Pyruvic Acid DrugBank PMID    (21 citations)
ConsensusPathDB - information on physical molecular interactions, biochemical pathways, and gene regulatory networks Drug interactions of PPI partners of ... P30613 ← explore drug target interactions of protein-protein-interaction partners
Protein information from multiple resources on PKLR (ENSG00000143627)
Target protein P30613 - KPYR_HUMAN
Description Pyruvate kinase isozymes R/L
Synonyms Red cell/liver pyruvate kinase - Pyruvate kinase 1 - R-type/L-type pyruvate kinase
iHOP - Information Hyperlinked over Proteins virtual access to literature search results P30613
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier KPYR_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number P30613
HUGO Gene Nomenclature Committee Gene Symbol PKLR
Ensembl: gene information Gene ID ENSG00000143627
Ensembl: protein information Protein IDs ENSP00000271946, ENSP00000339933
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000143627 --- ENST00000271946, ENST00000342741
PDB - A Resource for Studying Biological Macromolecules Structure Information 2VGF2VGG2VGI2VGB
Pfam database - a large collection of protein families Domain families PK_CPK
KEGG: Kyoto Encyclopedia of Genes and Genomes Gene ID 5313
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways P30613
SYSTERS release 4 - large-scale protein clustering based on sequence similarity for the entire organism space Protein Sequence Family 139399 (for P30613)
ConsensusPathDB - information on physical molecular interactions, biochemical pathways, and gene regulatory networks Protein-protein interaction (PPI) partners of ... P30613 ← Q15052 Q13153 P07195 P08559 P09622 P24298 P10515 P00338 P11177

Target protein B1AVT1 - B1AVT1_HUMAN
Description Pyruvate kinase
iHOP - Information Hyperlinked over Proteins virtual access to literature search results B1AVT1
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier B1AVT1_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number B1AVT1
HUGO Gene Nomenclature Committee Gene Symbol PKLR
Ensembl: gene information Gene ID ENSG00000143627
Ensembl: protein information Protein IDs ENSP00000408891, ENSP00000376214
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000143627 --- ENST00000423816, ENST00000423816
Pfam database - a large collection of protein families Domain families PK_CPK
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways B1AVT1

Target protein B1AVT2 - B1AVT2_HUMAN
Description Pyruvate kinase
iHOP - Information Hyperlinked over Proteins virtual access to literature search results B1AVT2
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier B1AVT2_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number B1AVT2
HUGO Gene Nomenclature Committee Gene Symbol PKLR
Ensembl: gene information Gene ID ENSG00000143627
Ensembl: protein information Protein ID ENSP00000271946
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000143627 --- ENST00000271946
Pfam database - a large collection of protein families Domain families PK_CPK
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways B1AVT2

Target protein B4DPM0 - B4DPM0_HUMAN
Description Pyruvate kinase
iHOP - Information Hyperlinked over Proteins virtual access to literature search results B4DPM0
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier B4DPM0_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number B4DPM0
HUGO Gene Nomenclature Committee Gene Symbol PKLR
Ensembl: gene information Gene ID ENSG00000143627
Ensembl: protein information Protein ID ENSP00000410319
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000143627 --- ENST00000452579
Pfam database - a large collection of protein families Domain families PK_CPK
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways B4DPM0

Target protein O75758 - O75758_HUMAN
Description Pyruvate kinase
iHOP - Information Hyperlinked over Proteins virtual access to literature search results O75758
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier O75758_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number O75758
HUGO Gene Nomenclature Committee Gene Symbol PKLR
Ensembl: gene information Gene ID ENSG00000143627
Ensembl: protein information Protein ID ENSP00000408891
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000143627 --- ENST00000423816
Pfam database - a large collection of protein families Domain families PK_CPK
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways O75758
SYSTERS release 4 - large-scale protein clustering based on sequence similarity for the entire organism space Protein Sequence Family 139399 (for O75758)

Target protein Q16715 - Q16715_HUMAN
Description Pyruvate kinase
iHOP - Information Hyperlinked over Proteins virtual access to literature search results Q16715
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier Q16715_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number Q16715
HUGO Gene Nomenclature Committee Gene Symbol PKLR
Ensembl: gene information Gene ID ENSG00000143627
Ensembl: protein information Protein ID ENSP00000271946
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000143627 --- ENST00000271946
Pfam database - a large collection of protein families Domain families PK_CPK
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways Q16715
SYSTERS release 4 - large-scale protein clustering based on sequence similarity for the entire organism space Protein Sequence Family 139399 (for Q16715)

Target protein Q16716 - Q16716_HUMAN
Description Pyruvate kinase
iHOP - Information Hyperlinked over Proteins virtual access to literature search results Q16716
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier Q16716_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number Q16716
HUGO Gene Nomenclature Committee Gene Symbol PKLR
Ensembl: gene information Gene ID ENSG00000143627
Ensembl: protein information Protein ID ENSP00000408891
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000143627 --- ENST00000423816
Pfam database - a large collection of protein families Domain families PK_CPK
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways Q16716
SYSTERS release 4 - large-scale protein clustering based on sequence similarity for the entire organism space Protein Sequence Family 139399 (for Q16716)