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Browse somatic cancers
by tissues or terms ...
NCI-60 cancer cell lines
Browse cancer-related
KEGG pathways ...
....
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gene identifiers
Browse cancer-related
KEGG pathways
Find targets by NCI-60
gene expression ...
... using a gene identifier
... using a KEGG pathway
... using significant
gene expression in 1 to 7
single NCI-60 cell lines
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differential gene expression ...
... within 2 NCI-60 cell lines
... from one own/external expression data set against one NCI-60 cell line
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... from two own/external expression data sets
(e.g., cancer/normal)
... from own/external expression data
using pre-calculated ratios
Connectivity Map ...
... explore drug influence on
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... using a compound identifier
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doi: 10.1093/nar/gkq910
Target search: 1 gene found
Egl nine homolog 1
(ENSG00000135766 - EGLN1 - Q9GZT9 A6XP74 Q9NTU9)
Cancer relevance of EGLN1 (ENSG00000135766)
Cancer-related Pathways for KEGG gene
54583
Renal cell carcinoma
Cancer-related Literature
609820
(phenotype)
606425
(gene)
Connectivity Map
Drug Treatment - Expression Data
ENSG00000135766
NCI-60
expression for ENSG00000135766
cancer cell lines
221497_x_at
NCI-60
expression of PPI partners of ...
ENSG00000135766
Drugs interacting with EGLN1 (ENSG00000135766)
Ascorbic Acid
DrugBank
PMID
(7 citations)
Protein information from multiple resources on EGLN1 (ENSG00000135766)
Target protein
Q9GZT9 - EGLN1_HUMAN
Description
Egl nine homolog 1
Synonyms
Prolyl hydroxylase domain-containing protein 2 - HIF-prolyl hydroxylase 2 - HIF-PH2 - Hypoxia-inducible factor prolyl hydroxylase 2 - SM-20 - PHD2 - HPH-2
virtual access to literature search results
Q9GZT9
Protein complex association
HIF1A-OS9-EGLN1 complex
Protein Identifier
EGLN1_HUMAN
Protein Accession Number
Q9GZT9
Gene Symbol
EGLN1
Gene ID
ENSG00000135766
Protein ID
ENSP00000355601
Variations (Gene as map --- transcript as list)
ENSG00000135766
---
ENST00000366641
Structure Information
3HQU
-
2HBT
-
2G1M
-
2G19
-
3HQR
-
2HBU
Domain families
zf-MYND
-
2OG-FeII_Oxy
Gene ID
54583
virtual access to biological pathways
Q9GZT9
Target protein
A6XP74 - A6XP74_HUMAN
virtual access to literature search results
A6XP74
Protein Identifier
A6XP74_HUMAN
Protein Accession Number
A6XP74
Gene Symbol
EGLN1
Gene ID
ENSG00000135766
Protein ID
ENSP00000355601
Variations (Gene as map --- transcript as list)
ENSG00000135766
---
ENST00000366641
Domain family
2OG-FeII_Oxy
virtual access to biological pathways
A6XP74
Target protein
Q9NTU9 - Q9NTU9_HUMAN
virtual access to literature search results
Q9NTU9
Protein Identifier
Q9NTU9_HUMAN
Protein Accession Number
Q9NTU9
Gene Symbol
EGLN1
Gene ID
ENSG00000135766
Protein ID
ENSP00000355601
Variations (Gene as map --- transcript as list)
ENSG00000135766
---
ENST00000366641
Domain family
2OG-FeII_Oxy
virtual access to biological pathways
Q9NTU9