Target search: 1 gene found

Interleukin-2 receptor subunit alpha (ENSG00000134460 - IL2RA - P01589 A2N4P8 A8MTT6 B2R9M9 O15163 Q53FH4 Q5W005 Q5W006)
Cancer relevance of IL2RA (ENSG00000134460)
KEGG: Kyoto Encyclopedia of Genes and GenomesCancer-related Pathways for KEGG gene 3559 Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
OMIM ® - Online Mendelian Inheritance in Man Cancer-related Literature 606367  (phenotype)
147730  (gene)
601942  (phenotype)
Cancer Types from drug target interaction databases leukemia, lung, lymphatic
Connectivity Map  info  Drug Treatment - Expression Data ENSG00000134460   info
NCI-60 expression for ENSG00000134460  info
 cancer cell lines                                                                                                                         
211269_s_at                                                                                                                        
206341_at                                                                                                                        
mean                                                                                                                        
ConsensusPathDB - information on physical molecular interactions, biochemical pathways, and gene regulatory networks NCI-60 expression of PPI partners of ... ENSG00000134460
Drugs interacting with IL2RA (ENSG00000134460)
denileukin diftitox TTD drug ID    DAP001098
DrugBank PMID    (7 citations)
Basiliximab DrugBank PMID    (7 citations)
Aldesleukin TTD drug ID    DAP001099
DrugBank PMID    (7 citations)
ConsensusPathDB - information on physical molecular interactions, biochemical pathways, and gene regulatory networks Drug interactions of PPI partners of ... P01589 ← explore drug target interactions of protein-protein-interaction partners
Protein information from multiple resources on IL2RA (ENSG00000134460)
Target protein P01589 - IL2RA_HUMAN
Description Interleukin-2 receptor subunit alpha
Synonyms IL-2R subunit alpha - IL2-RA - IL-2 receptor subunit alpha - TAC antigen - p55 - IL-2-RA
iHOP - Information Hyperlinked over Proteins virtual access to literature search results P01589
CORUM - the Comprehensive Resource of Mammalian protein complexes Protein complex association IL2-IL2RA-IL2RB complex
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier IL2RA_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number P01589
HUGO Gene Nomenclature Committee Gene Symbol IL2RA
Ensembl: gene information Gene ID ENSG00000134460
Ensembl: protein information Protein ID ENSP00000369293
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000134460 --- ENST00000379959
PDB - A Resource for Studying Biological Macromolecules Structure Information 3IU32B5I1ILM2ERJ1Z921ILN
Pfam database - a large collection of protein families Domain family Sushi
KEGG: Kyoto Encyclopedia of Genes and Genomes Gene ID 3559
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways P01589
SYSTERS release 4 - large-scale protein clustering based on sequence similarity for the entire organism space Protein Sequence Family 151099 (for P01589)
ConsensusPathDB - information on physical molecular interactions, biochemical pathways, and gene regulatory networks Protein-protein interaction (PPI) partners of ... P01589 ← P01589

Target protein A2N4P8 - A2N4P8_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results A2N4P8
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier A2N4P8_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number A2N4P8
HUGO Gene Nomenclature Committee Gene Symbol IL2RA
Ensembl: gene information Gene ID ENSG00000134460
Ensembl: protein information Protein ID ENSP00000369293
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000134460 --- ENST00000379959
Pfam database - a large collection of protein families Domain family Sushi
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways A2N4P8

Target protein A8MTT6 - A8MTT6_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results A8MTT6
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier A8MTT6_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number A8MTT6
HUGO Gene Nomenclature Committee Gene Symbol IL2RA
Ensembl: gene information Gene ID ENSG00000134460
Ensembl: protein information Protein ID ENSP00000380418
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000134460 --- ENST00000397243
Pfam database - a large collection of protein families Domain family Sushi
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways A8MTT6

Target protein B2R9M9 - B2R9M9_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results B2R9M9
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier B2R9M9_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number B2R9M9
HUGO Gene Nomenclature Committee Gene Symbol IL2RA
Ensembl: gene information Gene ID ENSG00000134460
Ensembl: protein information Protein ID ENSP00000369293
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000134460 --- ENST00000379959
Pfam database - a large collection of protein families Domain family Sushi
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways B2R9M9

Target protein O15163 - O15163_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results O15163
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier O15163_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number O15163
HUGO Gene Nomenclature Committee Gene Symbol IL2RA
Ensembl: gene information Gene ID ENSG00000134460
Ensembl: protein information Protein IDs ENSP00000380415, ENSP00000402024
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000134460 --- ENST00000397240, ENST00000397240
Pfam database - a large collection of protein families Domain family Sushi
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways O15163
SYSTERS release 4 - large-scale protein clustering based on sequence similarity for the entire organism space Protein Sequence Family 151099 (for O15163)

Target protein Q53FH4 - Q53FH4_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results Q53FH4
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier Q53FH4_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number Q53FH4
HUGO Gene Nomenclature Committee Gene Symbol IL2RA
Ensembl: gene information Gene ID ENSG00000134460
Ensembl: protein information Protein ID ENSP00000369293
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000134460 --- ENST00000379959
Pfam database - a large collection of protein families Domain family Sushi
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways Q53FH4

Target protein Q5W005 - Q5W005_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results Q5W005
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier Q5W005_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number Q5W005
HUGO Gene Nomenclature Committee Gene Symbol IL2RA
Ensembl: gene information Gene ID ENSG00000134460
Ensembl: protein information Protein ID ENSP00000369287
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000134460 --- ENST00000379954
Pfam database - a large collection of protein families Domain family Sushi
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways Q5W005

Target protein Q5W006 - Q5W006_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results Q5W006
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier Q5W006_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number Q5W006
HUGO Gene Nomenclature Committee Gene Symbol IL2RA
Ensembl: gene information Gene ID ENSG00000134460
Ensembl: protein information Protein ID ENSP00000256876
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000134460 --- ENST00000379954
Pfam database - a large collection of protein families Domain family Sushi
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways Q5W006