Target search: 1 gene found

GTPase KRas (ENSG00000133703 - KRAS - P01116 Q14014 Q14015)
Cancer relevance of KRAS (ENSG00000133703)
KEGG: Kyoto Encyclopedia of Genes and GenomesCancer-related Pathways for KEGG gene 3845 Acute myeloid leukemia
Bladder cancer
Chronic myeloid leukemia
Colorectal cancer
Endometrial cancer
ErbB signaling pathway
Glioma
Long-term depression
MAPK signaling pathway
Melanoma
Natural killer cell mediated cytotoxicity
Non-small cell lung cancer
Pancreatic cancer
Prostate cancer
Regulation of actin cytoskeleton
Renal cell carcinoma
T cell receptor signaling pathway
Thyroid cancer
Tight junction
VEGF signaling pathway
OMIM ® - Online Mendelian Inheritance in Man Cancer-related Literature 607785  (phenotype)
601626  (phenotype)
190070  (gene)
609942  (phenotype)
115150  (phenotype)
Cancer Types from drug target interaction databases colon, liver, lung, pancreatic, prostate, skin, uterus
Connectivity Map  info  Drug Treatment - Expression Data ENSG00000133703   info
NCI-60 expression for ENSG00000133703  info
 cancer cell lines                                                                                                                         
204010_s_at                                                                                                                        
214352_s_at                                                                                                                        
204009_s_at                                                                                                                        
mean                                                                                                                        
COSMIC - Catalogue of Somatic Mutations in Cancer NCI-60 Mutations
 cancer cell lines                                                                                                                         
Cell line link                                                                                                                        
Gene link                                                                                                                        
ConsensusPathDB - information on physical molecular interactions, biochemical pathways, and gene regulatory networks NCI-60 expression of PPI partners of ... ENSG00000133703
Drugs interacting with KRAS (ENSG00000133703)
allomaron PharmGKB PMID    (4 citations)
Asbestos CTD PMID    12725029
Fluorouracil CTD PMID    16803524
Genistein CTD PMID    15256057
irinotecan PharmGKB PMID    20177422
Quercetin CTD PMID    19424582
Vinyl Chloride CTD PMID    (3 citations)
ConsensusPathDB - information on physical molecular interactions, biochemical pathways, and gene regulatory networks Drug interactions of PPI partners of ... P01116 ← explore drug target interactions of protein-protein-interaction partners
Protein information from multiple resources on KRAS (ENSG00000133703)
Target protein P01116 - RASK_HUMAN
Description GTPase KRas
Synonyms Ki-Ras - GTPase KRas, N-terminally processed - c-Ki-ras - K-Ras 2 - c-K-ras
iHOP - Information Hyperlinked over Proteins virtual access to literature search results P01116
CORUM - the Comprehensive Resource of Mammalian protein complexes Protein complex association RAF1-RAS complex, EGF induced
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier RASK_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number P01116
HUGO Gene Nomenclature Committee Gene Symbol KRAS
Ensembl: gene information Gene ID ENSG00000133703
Ensembl: protein information Protein IDs ENSP00000379301, ENSP00000256078
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000133703 --- ENST00000256078
PDB - A Resource for Studying Biological Macromolecules Structure Information 1KZP1KZO1D8E1D8D3GFT
Pfam database - a large collection of protein families Domain family Ras
KEGG: Kyoto Encyclopedia of Genes and Genomes Gene ID 3845
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways P01116
SYSTERS release 4 - large-scale protein clustering based on sequence similarity for the entire organism space Protein Sequence Family 137502 (for P01116)
ConsensusPathDB - information on physical molecular interactions, biochemical pathways, and gene regulatory networks Protein-protein interaction (PPI) partners of ... P01116 ← P04049 P53609 P49354 P49356 P10415 P01112 P01116 P01111 Q02750 P36507 P15056 P04629

Target protein Q14014 - Q14014_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results Q14014
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier Q14014_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number Q14014
HUGO Gene Nomenclature Committee Gene Symbol KRAS
Ensembl: gene information Gene ID ENSG00000133703
Ensembl: protein information Protein IDs ENSP00000379301, ENSP00000256078, ENSP00000308495
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000133703 --- ENST00000256078, ENST00000256078, ENST00000311936
Pfam database - a large collection of protein families Domain family Ras
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways Q14014
SYSTERS release 4 - large-scale protein clustering based on sequence similarity for the entire organism space Protein Sequence Family 137502 (for Q14014)

Target protein Q14015 - Q14015_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results Q14015
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier Q14015_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number Q14015
HUGO Gene Nomenclature Committee Gene Symbol KRAS
Ensembl: gene information Gene ID ENSG00000133703
Ensembl: protein information Protein IDs ENSP00000379301, ENSP00000256078, ENSP00000308495
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000133703 --- ENST00000311936, ENST00000256078, ENST00000311936
Pfam database - a large collection of protein families Domain family Ras
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways Q14015
SYSTERS release 4 - large-scale protein clustering based on sequence similarity for the entire organism space Protein Sequence Family 137502 (for Q14015)