Target search: 1 gene found

DNA (cytosine-5)-methyltransferase 1 Cytosine-specific methyltransferase (ENSG00000130816 - DNMT1 - P26358 B3KVA0 Q59FP7)
Cancer relevance of DNMT1 (ENSG00000130816)
OMIM ® - Online Mendelian Inheritance in Man Cancer-related Literature 126375  (gene)
Cancer Types from drug target interaction databases bladder, colon, leukemia, skin, stomach, various
Connectivity Map  info  Drug Treatment - Expression Data ENSG00000130816   info
NCI-60 expression for ENSG00000130816  info
 cancer cell lines                                                                                                                         
201697_s_at                                                                                                                        
ConsensusPathDB - information on physical molecular interactions, biochemical pathways, and gene regulatory networks NCI-60 expression of PPI partners of ... ENSG00000130816
Drugs interacting with DNMT1 (ENSG00000130816)
Azacitidine CancerResource PMID    17612710
PharmGKB PMID    14627790
DrugBank PMID    (9 citations)
decitabine CancerResource PMID    (2 citations)
CTD PMID    (6 citations)
DrugBank PMID    (9 citations)
Flucytosine DrugBank PMID    (9 citations)
Genistein CTD PMID    19221000
Ifosfamide DrugBank PMID    (9 citations)
Procainamide DrugBank PMID    (9 citations)
ConsensusPathDB - information on physical molecular interactions, biochemical pathways, and gene regulatory networks Drug interactions of PPI partners of ... P26358 ← explore drug target interactions of protein-protein-interaction partners
Protein information from multiple resources on DNMT1 (ENSG00000130816)
Target protein P26358 - DNMT1_HUMAN
Description DNA (cytosine-5)-methyltransferase 1
Synonyms MCMT - Dnmt1 - CXXC-type zinc finger protein 9 - M.HsaI - DNA MTase HsaI - DNA methyltransferase HsaI
iHOP - Information Hyperlinked over Proteins virtual access to literature search results P26358
CORUM - the Comprehensive Resource of Mammalian protein complexes Protein complex association DNMT1-G9a-PCNA complex
DNMT1-G9a complex
pRb2/p130-multimolecular complex (DNMT1, E2F5, SuV39H1, HDAC1, RBL2)
DNMT1-RB1-HDAC1-E2F1 complex
DAXX-DNMT1-DMAP1 complex
RGS6-DNMT1-DMAP1 complex
pRb2/p130-multimolecular complex (DNMT1, E2F4, SuV39H1, HDAC1, RBL2)
TIP5-DNMT-HDAC1 complex
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier DNMT1_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number P26358
HUGO Gene Nomenclature Committee Gene Symbol DNMT1
Ensembl: gene information Gene ID ENSG00000130816
Ensembl: protein information Protein IDs ENSP00000345739, ENSP00000352516
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000130816 --- ENST00000340748, ENST00000359526
PDB - A Resource for Studying Biological Macromolecules Structure Information 3EPZ
Pfam database - a large collection of protein families Domain families zf-CXXCDMAP_bindingDNA_methylaseBAH
KEGG: Kyoto Encyclopedia of Genes and Genomes Gene ID 1786
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways P26358
SYSTERS release 4 - large-scale protein clustering based on sequence similarity for the entire organism space Protein Sequence Family 136808 (for P26358)
ConsensusPathDB - information on physical molecular interactions, biochemical pathways, and gene regulatory networks Protein-protein interaction (PPI) partners of ... P26358 ← Q9Y6K1 Q9UBC3 P63104 P26358

Target protein B3KVA0 - B3KVA0_HUMAN
Description Cytosine-specific methyltransferase
iHOP - Information Hyperlinked over Proteins virtual access to literature search results B3KVA0
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier B3KVA0_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number B3KVA0
HUGO Gene Nomenclature Committee Gene Symbol DNMT1
Ensembl: gene information Gene ID ENSG00000130816
Ensembl: protein information Protein IDs ENSP00000345739, ENSP00000352516
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000130816 --- ENST00000340748, ENST00000359526
Pfam database - a large collection of protein families Domain family DNA_methylase
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways B3KVA0

Target protein Q59FP7 - Q59FP7_HUMAN
Description Cytosine-specific methyltransferase
iHOP - Information Hyperlinked over Proteins virtual access to literature search results Q59FP7
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier Q59FP7_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number Q59FP7
HUGO Gene Nomenclature Committee Gene Symbol DNMT1
Ensembl: gene information Gene ID ENSG00000130816
Ensembl: protein information Protein ID ENSP00000345739
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000130816 --- ENST00000340748
Pfam database - a large collection of protein families Domain families zf-CXXCDMAP_bindingDNA_methylaseBAH
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways Q59FP7