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Browse somatic cancers
by tissues or terms ...
NCI-60 cancer cell lines
Browse cancer-related
KEGG pathways ...
....
Find target by gene identifier
Find targets by list of
gene identifiers
Browse cancer-related
KEGG pathways
Find targets by NCI-60
gene expression ...
... using a gene identifier
... using a KEGG pathway
... using significant
gene expression in 1 to 7
single NCI-60 cell lines
Find targets by
differential gene expression ...
... within 2 NCI-60 cell lines
... from one own/external expression data set against one NCI-60 cell line
... from one own/external expression data set to
determine the the closest NCI-60 cancer cell line
... from two own/external expression data sets
(e.g., cancer/normal)
... from own/external expression data
using pre-calculated ratios
Connectivity Map ...
... explore drug influence on
differential gene expression
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... by identifier
... by chemical property
... by structure
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in growth activity of NCI-60 cancer cell lines (cellular fingerprints) ...
... using a compound identifier
... of a compound group
... manually defining a
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... defining and searching by a compound structure
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biologically active against
a NCI-60 cancer cell line
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doi: 10.1093/nar/gkq910
Target search: 1 gene found
Xaa-Pro dipeptidase
(ENSG00000124299 - PEPD - P12955 A8K3Z1 A8K416 A8K696 A8MX47 B4DDB7)
Cancer relevance of PEPD (ENSG00000124299)
Cancer-related Literature
613230
(gene)
170100
(phenotype)
Connectivity Map
Drug Treatment - Expression Data
ENSG00000124299
NCI-60
expression for ENSG00000124299
cancer cell lines
202108_at
NCI-60
expression of PPI partners of ...
ENSG00000124299
Drugs interacting with PEPD (ENSG00000124299)
Doxorubicin
CancerResource
PMID
9798267
Adaphostin
PDB
structure
(2 ligand interactions)
Drug interactions of PPI partners of ...
P12955
← explore drug target interactions of protein-protein-interaction partners
Protein information from multiple resources on PEPD (ENSG00000124299)
Target protein
P12955 - PEPD_HUMAN
Description
Xaa-Pro dipeptidase
Synonyms
Proline dipeptidase - Imidodipeptidase - Peptidase D - Prolidase - X-Pro dipeptidase
virtual access to literature search results
P12955
Protein Identifier
PEPD_HUMAN
Protein Accession Number
P12955
Gene Symbol
PEPD
Gene ID
ENSG00000124299
Protein ID
ENSP00000244137
Variations (Gene as map --- transcript as list)
ENSG00000124299
---
ENST00000244137
Structure Information
2OKN
-
2IW2
Domain families
AMP_N
-
Peptidase_M24
Gene ID
5184
virtual access to biological pathways
P12955
Protein-protein interaction (PPI) partners of ...
P12955
← P12955
Target protein
A8K3Z1 - A8K3Z1_HUMAN
virtual access to literature search results
A8K3Z1
Protein Identifier
A8K3Z1_HUMAN
Protein Accession Number
A8K3Z1
Gene Symbol
PEPD
Gene ID
ENSG00000124299
Protein ID
ENSP00000244137
Variations (Gene as map --- transcript as list)
ENSG00000124299
---
ENST00000244137
Domain families
AMP_N
-
Peptidase_M24
virtual access to biological pathways
A8K3Z1
Target protein
A8K416 - A8K416_HUMAN
virtual access to literature search results
A8K416
Protein Identifier
A8K416_HUMAN
Protein Accession Number
A8K416
Gene Symbol
PEPD
Gene ID
ENSG00000124299
Protein ID
ENSP00000244137
Variations (Gene as map --- transcript as list)
ENSG00000124299
---
ENST00000244137
Domain families
AMP_N
-
Peptidase_M24
virtual access to biological pathways
A8K416
Target protein
A8K696 - A8K696_HUMAN
virtual access to literature search results
A8K696
Protein Identifier
A8K696_HUMAN
Protein Accession Number
A8K696
Gene Symbol
PEPD
Gene ID
ENSG00000124299
Protein ID
ENSP00000244137
Variations (Gene as map --- transcript as list)
ENSG00000124299
---
ENST00000244137
Domain families
AMP_N
-
Peptidase_M24
virtual access to biological pathways
A8K696
Target protein
A8MX47 - A8MX47_HUMAN
virtual access to literature search results
A8MX47
Protein Identifier
A8MX47_HUMAN
Protein Accession Number
A8MX47
Gene Symbol
PEPD
Gene ID
ENSG00000124299
Protein ID
ENSP00000380226
Variations (Gene as map --- transcript as list)
ENSG00000124299
---
ENST00000397032
Domain families
AMP_N
-
Peptidase_M24
virtual access to biological pathways
A8MX47
Target protein
B4DDB7 - B4DDB7_HUMAN
virtual access to literature search results
B4DDB7
Protein Identifier
B4DDB7_HUMAN
Protein Accession Number
B4DDB7
Gene Symbol
PEPD
Gene ID
ENSG00000124299
Protein ID
ENSP00000391890
Variations (Gene as map --- transcript as list)
ENSG00000124299
---
ENST00000436370
Domain families
AMP_N
-
Peptidase_M24
virtual access to biological pathways
B4DDB7