CancerResource
Home
Cancer
Drug
Target
Browse
About
Browse somatic cancers
by tissues or terms ...
NCI-60 cancer cell lines
Browse cancer-related
KEGG pathways ...
....
Find target by gene identifier
Find targets by list of
gene identifiers
Browse cancer-related
KEGG pathways
Find targets by NCI-60
gene expression ...
... using a gene identifier
... using a KEGG pathway
... using significant
gene expression in 1 to 7
single NCI-60 cell lines
Find targets by
differential gene expression ...
... within 2 NCI-60 cell lines
... from one own/external expression data set against one NCI-60 cell line
... from one own/external expression data set to
determine the the closest NCI-60 cancer cell line
... from two own/external expression data sets
(e.g., cancer/normal)
... from own/external expression data
using pre-calculated ratios
Connectivity Map ...
... explore drug influence on
differential gene expression
Find drugs ...
... by identifier
... by chemical property
... by structure
Find drugs by similarity
in growth activity of NCI-60 cancer cell lines (cellular fingerprints) ...
... using a compound identifier
... of a compound group
... manually defining a
cellular fingerprint
... defining and searching by a compound structure
Find drugs most
biologically active against
a NCI-60 cancer cell line
FAQ
HowTo
Statistics
Links
Contact
doi: 10.1093/nar/gkq910
Target search: 1 gene found
Cholinesterase
(ENSG00000114200 - BCHE - P06276 Q96HL2)
Cancer relevance of BCHE (ENSG00000114200)
Cancer-related Literature
177400
(gene+phenotype)
Cancer Types
from drug target interaction databases
prostate, uveal
Connectivity Map
Drug Treatment - Expression Data
ENSG00000114200
NCI-60
expression for ENSG00000114200
cancer cell lines
205433_at
NCI-60
expression of PPI partners of ...
ENSG00000114200
Drugs interacting with BCHE (ENSG00000114200)
bicalutamide
CTD
PMID
15638997
Butyric Acid
DrugBank
PMID
(7 citations)
Choline
DrugBank
PMID
(7 citations)
demecarium bromide
DrugBank
PMID
(7 citations)
Echothiophate Iodide
TTD
drug ID
DAP000962
DrugBank
PMID
(7 citations)
Genistein
CTD
PMID
15378649
hexafluorenium
DrugBank
PMID
(7 citations)
Isoflurophate
DrugBank
PMID
(7 citations)
Drug interactions of PPI partners of ...
P06276
← explore drug target interactions of protein-protein-interaction partners
Protein information from multiple resources on BCHE (ENSG00000114200)
Target protein
P06276 - CHLE_HUMAN
Description
Cholinesterase
Synonyms
Pseudocholinesterase - Choline esterase II - Acylcholine acylhydrolase - Butyrylcholine esterase
virtual access to literature search results
P06276
Protein Identifier
CHLE_HUMAN
Protein Accession Number
P06276
Gene Symbol
BCHE
Gene ID
ENSG00000114200
Protein ID
ENSP00000264381
Variations (Gene as map --- transcript as list)
ENSG00000114200
---
ENST00000264381
Structure Information
2WSL
-
2J4C
-
2WIK
-
1KCJ
-
1XLU
-
1P0P
-
2WIJ
-
1XLV
-
1EHO
-
1P0M
-
2PM8
-
1XLW
-
1EHQ
-
1P0Q
-
2WID
-
2WIL
-
3DJY
-
2WIF
-
3DKK
-
1P0I
-
2WIG
Domain families
COesterase
-
AChE_tetra
Gene ID
590
virtual access to biological pathways
P06276
Protein-protein interaction (PPI) partners of ...
P06276
← P06276
Target protein
Q96HL2 - Q96HL2_HUMAN
virtual access to literature search results
Q96HL2
Protein Identifier
Q96HL2_HUMAN
Protein Accession Number
Q96HL2
Gene Symbol
BCHE
Gene ID
ENSG00000114200
Protein IDs
ENSP00000264381
,
ENSP00000418325
Variations (Gene as map --- transcript as list)
ENSG00000114200
---
ENST00000264381
,
ENST00000479451
Domain family
AChE_tetra
virtual access to biological pathways
Q96HL2