Target search: 1 gene found

Amiloride-sensitive sodium channel subunit alpha (ENSG00000111319 - SCNN1A - P37088 B4E2Q5 C5HTY8 C5HTY9 C5HTZ1 Q6UP09)
Cancer relevance of SCNN1A (ENSG00000111319)
OMIM ® - Online Mendelian Inheritance in Man Cancer-related Literature 264350  (phenotype)
613021  (phenotype)
600228  (gene)
Cancer Types from drug target interaction databases skin, various
Connectivity Map  info  Drug Treatment - Expression Data ENSG00000111319   info
NCI-60 expression for ENSG00000111319  info
 cancer cell lines                                                                                                                         
215026_x_at                                                                                                                        
217264_s_at                                                                                                                        
203453_at                                                                                                                        
mean                                                                                                                        
Drugs interacting with SCNN1A (ENSG00000111319)
alitretinoin CTD PMID    16168501
Amiloride DrugBank PMID    (11 citations)
cycloteriam DrugBank PMID    (11 citations)
Protein information from multiple resources on SCNN1A (ENSG00000111319)
Target protein P37088 - SCNNA_HUMAN
Description Amiloride-sensitive sodium channel subunit alpha
Synonyms Nonvoltage-gated sodium channel 1 subunit alpha - SCNEA - Alpha-ENaC - Alpha-NaCH - ENaCA - Epithelial Na(+) channel subunit alpha
iHOP - Information Hyperlinked over Proteins virtual access to literature search results P37088
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier SCNNA_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number P37088
HUGO Gene Nomenclature Committee Gene Symbol SCNN1A
Ensembl: gene information Gene ID ENSG00000111319
Ensembl: protein information Protein IDs ENSP00000228916, ENSP00000353292, ENSP00000380166
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000111319 --- ENST00000360168, ENST00000396966
Pfam database - a large collection of protein families Domain family ASC
KEGG: Kyoto Encyclopedia of Genes and Genomes Gene ID 6337
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways P37088
SYSTERS release 4 - large-scale protein clustering based on sequence similarity for the entire organism space Protein Sequence Family 137609 (for P37088)

Target protein B4E2Q5 - B4E2Q5_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results B4E2Q5
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier B4E2Q5_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number B4E2Q5
HUGO Gene Nomenclature Committee Gene Symbol SCNN1A
Ensembl: gene information Gene ID ENSG00000111319
Ensembl: protein information Protein ID ENSP00000353292
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000111319 --- ENST00000360168
Pfam database - a large collection of protein families Domain family ASC
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways B4E2Q5

Target protein C5HTY8 - C5HTY8_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results C5HTY8
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier C5HTY8_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number C5HTY8
HUGO Gene Nomenclature Committee Gene Symbol SCNN1A
Ensembl: gene information Gene ID ENSG00000111319
Ensembl: protein information Protein ID ENSP00000353292
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000111319 --- ENST00000360168
Pfam database - a large collection of protein families Domain family ASC
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways C5HTY8

Target protein C5HTY9 - C5HTY9_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results C5HTY9
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier C5HTY9_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number C5HTY9
HUGO Gene Nomenclature Committee Gene Symbol SCNN1A
Ensembl: gene information Gene ID ENSG00000111319
Ensembl: protein information Protein ID ENSP00000351825
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000111319 --- ENST00000358945
Pfam database - a large collection of protein families Domain family ASC
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways C5HTY9

Target protein C5HTZ1 - C5HTZ1_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results C5HTZ1
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier C5HTZ1_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number C5HTZ1
HUGO Gene Nomenclature Committee Gene Symbol SCNN1A
Ensembl: gene information Gene ID ENSG00000111319
Ensembl: protein information Protein ID ENSP00000345028
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000111319 --- ENST00000338748
Pfam database - a large collection of protein families Domain family ASC
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways C5HTZ1

Target protein Q6UP09 - Q6UP09_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results Q6UP09
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier Q6UP09_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number Q6UP09
HUGO Gene Nomenclature Committee Gene Symbol SCNN1A
Ensembl: gene information Gene ID ENSG00000111319
Ensembl: protein information Protein ID ENSP00000353292
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000111319 --- ENST00000360168
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways Q6UP09