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Browse somatic cancers
by tissues or terms ...
NCI-60 cancer cell lines
Browse cancer-related
KEGG pathways ...
....
Find target by gene identifier
Find targets by list of
gene identifiers
Browse cancer-related
KEGG pathways
Find targets by NCI-60
gene expression ...
... using a gene identifier
... using a KEGG pathway
... using significant
gene expression in 1 to 7
single NCI-60 cell lines
Find targets by
differential gene expression ...
... within 2 NCI-60 cell lines
... from one own/external expression data set against one NCI-60 cell line
... from one own/external expression data set to
determine the the closest NCI-60 cancer cell line
... from two own/external expression data sets
(e.g., cancer/normal)
... from own/external expression data
using pre-calculated ratios
Connectivity Map ...
... explore drug influence on
differential gene expression
Find drugs ...
... by identifier
... by chemical property
... by structure
Find drugs by similarity
in growth activity of NCI-60 cancer cell lines (cellular fingerprints) ...
... using a compound identifier
... of a compound group
... manually defining a
cellular fingerprint
... defining and searching by a compound structure
Find drugs most
biologically active against
a NCI-60 cancer cell line
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doi: 10.1093/nar/gkq910
Target search: 1 gene found
Cystatin-C
(ENSG00000101439 - CST3 - P01034)
Cancer relevance of CST3 (ENSG00000101439)
Cancer-related Literature
604312
(gene)
105150
(phenotype)
611953
(phenotype)
Cancer Types
from drug target interaction databases
leukemia
Connectivity Map
Drug Treatment - Expression Data
ENSG00000101439
NCI-60
expression for ENSG00000101439
No query result. No gene or expression corresponding to input found in database ...
NCI-60
expression of PPI partners of ...
ENSG00000101439
Drugs interacting with CST3 (ENSG00000101439)
decitabine
CTD
PMID
17330099
vorinostat
CTD
PMID
17330099
Drug interactions of PPI partners of ...
P01034
← explore drug target interactions of protein-protein-interaction partners
Protein information from multiple resources on CST3 (ENSG00000101439)
Target protein
P01034 - CYTC_HUMAN
Description
Cystatin-C
Synonyms
Post-gamma-globulin - Gamma-trace - Neuroendocrine basic polypeptide - Cystatin-3
virtual access to literature search results
P01034
Protein Identifier
CYTC_HUMAN
Protein Accession Number
P01034
Gene Symbol
CST3
Gene ID
ENSG00000101439
Protein IDs
ENSP00000366124
,
ENSP00000381446
,
ENSP00000381448
Variations (Gene as map --- transcript as list)
ENSG00000101439
---
ENST00000398409
,
ENST00000398409
Structure Information
1G96
-
1TIJ
-
1R4C
-
3GAX
Domain family
Cystatin
Gene ID
1471
virtual access to biological pathways
P01034
Protein-protein interaction (PPI) partners of ...
P01034
← P07858