Target search: 1 gene found

RNA-binding protein FUS (ENSG00000089280 - FUS - P35637 A6NMX6 A8K4H1 B4DR70 B4DVJ7 Q13344 Q6IBQ5 Q8TBR3)
Cancer relevance of FUS (ENSG00000089280)
OMIM ® - Online Mendelian Inheritance in Man Cancer-related Literature 612160  (phenotype)
608030  (phenotype)
137070  (gene)
Cancer Types from drug target interaction databases breast, lung, skin, uterus
Connectivity Map  info  Drug Treatment - Expression Data ENSG00000089280   info
NCI-60 expression for ENSG00000089280  info
 cancer cell lines                                                                                                                         
200959_at                                                                                                                        
217370_x_at                                                                                                                        
mean                                                                                                                        
ConsensusPathDB - information on physical molecular interactions, biochemical pathways, and gene regulatory networks NCI-60 expression of PPI partners of ... ENSG00000089280
Drugs interacting with FUS (ENSG00000089280)
Cisplatin PharmGKB PMID    (2 citations)
gefitinib PharmGKB PMID    18379348
Tamoxifen CTD PMID    16202921
ConsensusPathDB - information on physical molecular interactions, biochemical pathways, and gene regulatory networks Drug interactions of PPI partners of ... P35637 ← explore drug target interactions of protein-protein-interaction partners
Protein information from multiple resources on FUS (ENSG00000089280)
Target protein P35637 - FUS_HUMAN
Description RNA-binding protein FUS
Synonyms Oncogene FUS - Translocated in liposarcoma protein - POMp75 - Oncogene TLS - 75 kDa DNA-pairing protein
iHOP - Information Hyperlinked over Proteins virtual access to literature search results P35637
CORUM - the Comprehensive Resource of Mammalian protein complexes Protein complex association Large Drosha complex
DGCR8 multiprotein complex
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier FUS_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number P35637
HUGO Gene Nomenclature Committee Gene Symbol FUS
Ensembl: gene information Gene ID ENSG00000089280
Ensembl: protein information Protein ID ENSP00000254108
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000089280 --- ENST00000254108
Pfam database - a large collection of protein families Domain families zf-RanBPRRM_1
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways P35637
SYSTERS release 4 - large-scale protein clustering based on sequence similarity for the entire organism space Protein Sequence Family 139037 (for P35637)
ConsensusPathDB - information on physical molecular interactions, biochemical pathways, and gene regulatory networks Protein-protein interaction (PPI) partners of ... P35637 ← P49841 P52565 P10827 O15399 Q05586 P35637

Target protein A6NMX6 - A6NMX6_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results A6NMX6
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier A6NMX6_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number A6NMX6
HUGO Gene Nomenclature Committee Gene Symbol FUS
Ensembl: gene information Gene ID ENSG00000089280
Ensembl: protein information Protein ID ENSP00000369594
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000089280 --- ENST00000380244
Pfam database - a large collection of protein families Domain family RRM_1
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways A6NMX6

Target protein A8K4H1 - A8K4H1_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results A8K4H1
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier A8K4H1_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number A8K4H1
HUGO Gene Nomenclature Committee Gene Symbol FUS
Ensembl: gene information Gene ID ENSG00000089280
Ensembl: protein information Protein ID ENSP00000254108
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000089280 --- ENST00000254108
Pfam database - a large collection of protein families Domain families zf-RanBPRRM_1
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways A8K4H1

Target protein B4DR70 - B4DR70_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results B4DR70
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier B4DR70_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number B4DR70
HUGO Gene Nomenclature Committee Gene Symbol FUS
Ensembl: gene information Gene ID ENSG00000089280
Ensembl: protein information Protein ID ENSP00000378041
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000089280 --- ENST00000254108
Pfam database - a large collection of protein families Domain families zf-RanBPRRM_1
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways B4DR70

Target protein B4DVJ7 - B4DVJ7_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results B4DVJ7
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier B4DVJ7_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number B4DVJ7
HUGO Gene Nomenclature Committee Gene Symbol FUS
Ensembl: gene information Gene ID ENSG00000089280
Ensembl: protein information Protein ID ENSP00000396348
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000089280 --- ENST00000254108
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways B4DVJ7

Target protein Q13344 - Q13344_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results Q13344
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier Q13344_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number Q13344
HUGO Gene Nomenclature Committee Gene Symbol FUS
Ensembl: gene information Gene ID ENSG00000089280
Ensembl: protein information Protein ID ENSP00000395493
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000089280 --- ENST00000433338
Pfam database - a large collection of protein families Domain families zf-RanBPRRM_1
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways Q13344
SYSTERS release 4 - large-scale protein clustering based on sequence similarity for the entire organism space Protein Sequence Family 139037 (for Q13344)

Target protein Q6IBQ5 - Q6IBQ5_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results Q6IBQ5
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier Q6IBQ5_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number Q6IBQ5
HUGO Gene Nomenclature Committee Gene Symbol FUS
Ensembl: gene information Gene ID ENSG00000089280
Ensembl: protein information Protein ID ENSP00000254108
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000089280 --- ENST00000254108
Pfam database - a large collection of protein families Domain families zf-RanBPRRM_1
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways Q6IBQ5

Target protein Q8TBR3 - Q8TBR3_HUMAN
iHOP - Information Hyperlinked over Proteins virtual access to literature search results Q8TBR3
UniProt - Protein knowledgebase (UniProtKB) Protein Identifier Q8TBR3_HUMAN
UniProt - Protein knowledgebase (UniProtKB) Protein Accession Number Q8TBR3
HUGO Gene Nomenclature Committee Gene Symbol FUS
Ensembl: gene information Gene ID ENSG00000089280
Ensembl: protein information Protein ID ENSP00000254108
Ensembl: information about variations in genes and transcripts Variations (Gene as map --- transcript as list) ENSG00000089280 --- ENST00000254108
Pfam database - a large collection of protein families Domain families zf-RanBPRRM_1
Reactome - a curated knowledgebase of biological pathways virtual access to biological pathways Q8TBR3
SYSTERS release 4 - large-scale protein clustering based on sequence similarity for the entire organism space Protein Sequence Family 139037 (for Q8TBR3)